Porosity Overview

The range of separation of a GPC column is determined through its porosity. Several columns can be combined to get good separation over a broad size range.

Porosity class *)AppliChrom rangetraditionalSeparation range
100

100 – 2.500 Da100 Å100 - 4.000 Da
200100 – 20.000 Da500 Å500 – 30.000 Da
100 – 70.000 Da1000 Å500 – 60.000 Da
3001 kDa – 300 kDa10e4 Å1 kDa – 600 kDa
4002,5 kDa – 1.000 kDa10e5 Å50 kDa – 2.000 kDa
50010 kDa – 5.000 kDa500 kDa – 10.000 kDa
screening100 Da – 1 mio Da
*) Porosity typically valid for column size 300 x 8mm